Age-related neuropathology, cognitive decline, and Alzheimer's disease

@article{Keller2006AgerelatedNC,
  title={Age-related neuropathology, cognitive decline, and Alzheimer's disease},
  author={Jeffrey N. Keller},
  journal={Ageing Research Reviews},
  year={2006},
  volume={5},
  pages={1-13}
}
In the last 20 years, there have been tremendous strides made in the understanding of the molecular and cellular processes that occur during brain aging, as well as our understanding of age-related disorders of the central nervous system (CNS). Aging is associated with a decline in cognitive performance, and is the biggest risk factor for the development of Alzheimer's disease (AD), although the underlying basis for both of these observations is poorly defined. Both normal aging and AD are… CONTINUE READING
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