Age-related neural activity during allocentric spatial memory.

@article{Antonova2009AgerelatedNA,
  title={Age-related neural activity during allocentric spatial memory.},
  author={Elena Antonova and David Parslow and M. F. Brammer and Gerard R. Dawson and Stephen H. D. Jackson and Robin G. Morris},
  journal={Memory},
  year={2009},
  volume={17 2},
  pages={
          125-43
        }
}
Age-related decline in allocentric (viewer-independent) spatial memory is seen across species. We employed a virtual reality analogue of the Morris Water Maze to study the effect of healthy ageing on neural activity during allocentric spatial memory using functional magnetic resonance imaging. Voxel-based morphometry was used to ascertain hippocampal volumetric integrity. A widespread neural network comprising frontal, parietal, occipital, thalamic, and cerebellar regions was activated in young… CONTINUE READING
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