Age-related macular degeneration

@article{Mitchell2018AgerelatedMD,
  title={Age-related macular degeneration},
  author={P Mitchell and Gerald M. Liew and Bamini Gopinath and Tien Yin Wong},
  journal={The Lancet},
  year={2018},
  volume={392},
  pages={1147-1159}
}
Age-related macular degeneration is a leading cause of visual impairment and severe vision loss. Clinically, it is classified as early-stage (medium-sized drusen and retinal pigmentary changes) to late-stage (neovascular and atrophic). Age-related macular degeneration is a multifactorial disorder, with dysregulation in the complement, lipid, angiogenic, inflammatory, and extracellular matrix pathways implicated in its pathogenesis. More than 50 genetic susceptibility loci have been identified… CONTINUE READING
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