Age-related losses of retinal ganglion cells and axons.

  title={Age-related losses of retinal ganglion cells and axons.},
  author={Ronald S. Harwerth and Joe L. Wheat and Nalini V Rangaswamy},
  journal={Investigative ophthalmology & visual science},
  volume={49 10},
PURPOSE Age-related losses in retinal nerve fiber layer (RNFL) thickness have been assumed to be the result of an age-dependent reduction of retinal ganglion cells (RGCs), but the published rates differ: age-related losses of RGCs of approximately 0.6%/year compared to 0.2%/year for thinning of the RNFL. An analysis of normative data for standard automated perimetry (SAP) sensitivities and optical coherence tomography (OCT) measures of RNFL thickness showed that the apparent disagreement in age… CONTINUE READING
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