Age-related loss of the responsiveness of the tuberoinfundibular dopaminergic neurons to prolactin in the female rat.


In the old female rat the previous findings of a sustained reduction of the secretory activity of the hypothalamic tuberoinfundibular dopaminergic (TIDA) neurons associated with a persistent hyperprolactinemia as well as the observation of a failure of the prolactin (PRL) short-loop feedback mechanism have been suggestive of an age-related loss of the… (More)


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