Age-related enhancement of 5-lipoxygenase metabolic capacity in cattle alveolar macrophages.

@article{Lu1996AgerelatedEO,
  title={Age-related enhancement of 5-lipoxygenase metabolic capacity in cattle alveolar macrophages.},
  author={Michael C. Lu and Marc Peters-Golden and Douglas E Hostetler and Norman Edward Robinson and Frederik J. Derksen},
  journal={The American journal of physiology},
  year={1996},
  volume={271 4 Pt 1},
  pages={L547-54}
}
Arachidonic acid (AA) metabolism was assessed in cultured alveolar macrophages (AM) obtained from newborn (9- and 23-day-old) and adult (2- and 6-yr-old) cattle. The AM were prelabeled in [3H]AA-containing medium and, thereafter, stimulated with either A-23187 or zymosan. The released radiolabeled AA metabolites were measured by high-performance liquid… CONTINUE READING