Age-related effects of acute nicotine on behavioural and neuronal measures of anxiety.

@article{Kupferschmidt2010AgerelatedEO,
  title={Age-related effects of acute nicotine on behavioural and neuronal measures of anxiety.},
  author={David A Kupferschmidt and Douglas Funk and Suzanne Erb and Anh Dzung L{\^e}},
  journal={Behavioural brain research},
  year={2010},
  volume={213 2},
  pages={288-92}
}
Adolescence is considered a period of enhanced vulnerability to the initiation of tobacco use. Biological differences in the sensitivity of adolescents and adults to the anxiogenic and anxiolytic effects of nicotine may contribute to this heightened vulnerability. Here, we investigated the age-dependency of the effects of acute nicotine on anxiety-related behaviour and neurotransmission. In Experiment 1, male adolescent (P33-37) and adult (P65-69) Long-Evans rats received nicotine (0, 0.4 or 0… CONTINUE READING