Age-related disorders of sleep and motor control in the rat models of functionally distinct cholinergic neuropathology.

@article{Ciric2016AgerelatedDO,
  title={Age-related disorders of sleep and motor control in the rat models of functionally distinct cholinergic neuropathology.},
  author={Jelena Ciric and Katarina Lazic and Jelena Petrovi{\'c} and A. Kalauzi and Jasna Saponjic},
  journal={Behavioural brain research},
  year={2016},
  volume={301},
  pages={273-86}
}
We studied the impact of aging during sleep in the rat models of Alzheimer's (AD) and Parkinson's (PD) disease cholinergic neuropathology to determine the possible different and earlier onset of age-related sleep disorder during the neurodegenerative diseases vs. healthy aging. We used the bilateral nucleus basalis (NB) and pedunculopontine tegmental nucleus (PPT) lesioned rats as the in vivo models of functionally distinct cholinergic neuropathology, and we followed the impact of aging on… CONTINUE READING
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