Age-related differences in the sensitivity of the fish immune response to a coplanar PCB.

@article{Duffy2003AgerelatedDI,
  title={Age-related differences in the sensitivity of the fish immune response to a coplanar PCB.},
  author={Jessica E Duffy and Erik A Carlson and Yiqiang Li and Colette M Prophete and J T Zelikofft},
  journal={Ecotoxicology},
  year={2003},
  volume={12 1-4},
  pages={251-9}
}
Polychlorinated biphenyls (PCBs) are widespread environmental pollutants. Because of their persistence and bioaccumulation in aquatic organisms (among other factors), the biological impact of PCB exposure on resident fish populations is of particular concern. To assess the effect(s) of an environmentally relevant coplanar PCB congener on the fish immune response, juvenile and aged Japanese medaka (Oryzias latipes) were injected i.p. with either vehicle or PCB 126 (at 0.01 or 1.0 microg/g BW… CONTINUE READING