Age-related differences in the sympathetic-hemodynamic balance in men.

  title={Age-related differences in the sympathetic-hemodynamic balance in men.},
  author={Emma C. J. Hart and Michael J. Joyner and B. G. Wallin and Christopher Peter Johnson and Timothy B. Curry and John H. Eisenach and Nisha Charkoudian},
  volume={54 1},
As humans age, the tonic level of activity in sympathetic vasoconstrictor nerves increases and may contribute to age-related increases in blood pressure. In previous studies in normotensive young men with varying levels of resting sympathetic nerve activity, we observed a balance among factors contributing to blood pressure regulation, such that higher sympathetic activity was associated with lower cardiac output and lesser vascular responsiveness to alpha-adrenergic agonists, which limited the… CONTINUE READING
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