Age-related differences in expression of signal differentiation factors for human thymic epithelial cells

Abstract

Expression of transcription proteins PAX1, Hoxa3, and TLP regulating differentiation of thymic epithelial cells is detected in human thymus starting from gestation week 22 until the age of 95 years. Expression of transcription factors significantly decreased during aging. Apart from the decrease in the expression of signal differentiation factors in… (More)
DOI: 10.1007/s10517-007-0298-1

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