Age-related decline of myelin proteins is highly correlated with activation of astrocytes and microglia in the rat CNS.

@article{Xie2013AgerelatedDO,
  title={Age-related decline of myelin proteins is highly correlated with activation of astrocytes and microglia in the rat CNS.},
  author={Fang Xie and Jiu-Cong Zhang and Han Liang Fu and Jun Chen},
  journal={International journal of molecular medicine},
  year={2013},
  volume={32 5},
  pages={1021-8}
}
It has been shown that aging can greatly influence the integrity and ultrastructure of white matter and the myelin sheath; however, studies regarding the effects of aging on the expression of myelin proteins are still limited. In the present study, immunohistochemical mapping was used to investigate the overall expression of myelin basic protein (Mbp) and myelin oligodendrocyte glycoprotein (Mog) in the central nervous system (CNS) of rats in postnatal months 2, 5, 18 and 26. Astrocyte and… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 35 references

Human brain myelination trajectories across the life span: implications for CNS function and dysfunction

  • JE Sherin, G Bartzokis
  • Masoro EJ and Austa SN (eds). 7th edition
  • 2011
1 Excerpt

Glial cells: astrocytes and oligodendrocytes during normal brain aging. In: Handbook of the Neuroscience of Aging

  • I Blasco, C Humpel, B Grubeck-Loebenstein
  • Hof PR and Mobbs CV (eds)
  • 2009
1 Excerpt

The effects of normal aging on myelinated nerve fibers in monkey central nervous system

  • A Peters
  • Front Neuroanat
  • 2009
1 Excerpt

Similar Papers

Loading similar papers…