Age-related circadian disorganization caused by sympathetic dysfunction in peripheral clock regulation

Abstract

The ability of the circadian clock to adapt to environmental changes is critical for maintaining homeostasis, preventing disease, and limiting the detrimental effects of aging. To date, little is known about age-related changes in the entrainment of peripheral clocks to external cues. We therefore evaluated the ability of the peripheral clocks of the kidney… (More)
DOI: 10.1038/npjamd.2016.30

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