Age-related changes of serum sex hormones, insulin-like growth factor-1 and sex-hormone binding globulin levels in men: cross-sectional data from a healthy male cohort.

@article{Leifke2000AgerelatedCO,
  title={Age-related changes of serum sex hormones, insulin-like growth factor-1 and sex-hormone binding globulin levels in men: cross-sectional data from a healthy male cohort.},
  author={Eckhard Leifke and Vitali Gorenoi and C Wichers and Alexander von zur M{\"u}hlen and E von B{\"u}ren and Georg Brabant},
  journal={Clinical endocrinology},
  year={2000},
  volume={53 6},
  pages={
          689-95
        }
}
The age-dependent decline of the gonadal and somatotopic axis has been causally linked to frailty in the elderly by their effects on muscle mass and bone mineral density. However, for healthy men data on serum oestrogens and androgens, as well as IGF-1, as a common outcome measure covering the whole adult age range are scarce. We therefore studied healthy, nonobese male subjects between 20 and 80 years of age to asses their morning concentrations of total (T), free (FT), bioavailable… CONTINUE READING

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