Age-related changes in total DNA and RNA and incorporation of uridine and thymidine in rat liver, kidney and spleen.

@article{Messineo1983AgerelatedCI,
  title={Age-related changes in total DNA and RNA and incorporation of uridine and thymidine in rat liver, kidney and spleen.},
  author={L. Messineo and Charles W. Denko and Mark Petricevic},
  journal={The International journal of biochemistry},
  year={1983},
  volume={15 9},
  pages={1103-7}
}
Total content of DNA and RNA in liver, kidney and spleen were measured in young and aged rats. At the same time the incorporation of [14C]thymidine, a DNA precursor, and [3H]uridine, an RNA precursor, were also determined. Changes in total organ DNA and RNA correlated with sexual maturation as did incorporation of precursors. Young animals have more DNA per… CONTINUE READING