Age-related changes in the topological architecture of the brain during hand grip

  title={Age-related changes in the topological architecture of the brain during hand grip},
  author={Chang-hyun Park and Marie-H{\'e}l{\`e}ne Boudrias and Holly E. Rossiter and Nick S. Ward},
  booktitle={Neurobiology of Aging},
Neuroanatomical changes in the aging brain are widely distributed rather than focal. We investigated age-related changes in large-scale functional brain networks by applying graph theory to functional magnetic resonance imaging data acquired during a simple grip task with either dominant or nondominant hand. We measured the effect of age on efficiency of information transfer within a series of hierarchical functional networks composed of the whole brain or component parts of the whole brain… CONTINUE READING

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