Age-related changes in the static and dynamic mechanical properties of mouse lungs.

@article{Hirai1995AgerelatedCI,
  title={Age-related changes in the static and dynamic mechanical properties of mouse lungs.},
  author={T. Hirai and M. Hosokawa and K. Kawakami and Y. Takubo and N. Sakai and Y. Oku and K. Chin and M. Ohi and K. Higuchi and K. Kuno},
  journal={Respiration physiology},
  year={1995},
  volume={102 2-3},
  pages={
          195-203
        }
}
  • T. Hirai, M. Hosokawa, +7 authors K. Kuno
  • Published 1995
  • Chemistry, Medicine
  • Respiration physiology
  • To investigate the effects of aging on pulmonary mechanical properties in mice, we devised a new experimental apparatus to measure the respiratory impedance of excised lungs in mice and examined age-related changes in both static and dynamic properties. In an accelerated senescence-resistant strain of mice, SAMR1 (Takeda, T., Y. Fukuchi, Y. Uejima, K. Teramoto, T. Oka and H. Orino, J. Am. Geriatr. Soc. 39: 911-919, 1991), ranging from 3 to 24 months of age, static compliance (Cst) as well as… CONTINUE READING
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