Age-related changes in the proteostasis network in the brain of the naked mole-rat: Implications promoting healthy longevity.

@article{Triplett2015AgerelatedCI,
  title={Age-related changes in the proteostasis network in the brain of the naked mole-rat: Implications promoting healthy longevity.},
  author={Judy C. Triplett and Antonella Tramutola and Aaron M. Swomley and Jessime M Kirk and Kelly M. Grimes and Kaitilyn N. Lewis and Miranda E. Orr and Karl A. Rodriguez and Jian Cai and Jon B. Klein and Marzia Perluigi and Rochelle Buffenstein and David Butterfield},
  journal={Biochimica et biophysica acta},
  year={2015},
  volume={1852 10 Pt A},
  pages={
          2213-24
        }
}
The naked mole-rat (NMR) is the longest-lived rodent and possesses several exceptional traits: marked cancer resistance, negligible senescence, prolonged genomic integrity, pronounced proteostasis, and a sustained health span. The underlying molecular mechanisms that contribute to these extraordinary attributes are currently under investigation to gain… CONTINUE READING