Age-related changes in the morphology and deformational behavior of knee joint cartilage.

@article{Hudelmaier2001AgerelatedCI,
  title={Age-related changes in the morphology and deformational behavior of knee joint cartilage.},
  author={Martin I Hudelmaier and Christian Glaser and Jan Hohe and K. H. Englmeier and Maximilian Reiser and Reinhard Putz and Felix Eckstein},
  journal={Arthritis and rheumatism},
  year={2001},
  volume={44 11},
  pages={2556-61}
}
OBJECTIVE Alterations of cartilage morphology and mechanical properties occur in osteoarthritis, but it is unclear whether similar changes also take place physiologically during aging, in the absence of disease. In this in vivo study, we tested the hypothesis that thinning of knee joint cartilage occurs with aging and that elderly subjects display a different amount of cartilage deformation than do young subjects. METHODS We evaluated 30 asymptomatic subjects ages 50-78 years. Morphologic… CONTINUE READING

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