Age-related changes in the expression of Alzheimer's beta APP in the brain of senescence accelerated mouse (SAM)-P/10.

@article{Jeong1997AgerelatedCI,
  title={Age-related changes in the expression of Alzheimer's beta APP in the brain of senescence accelerated mouse (SAM)-P/10.},
  author={Sook-Hyang Jeong and Kyungjin Kim and Young Ho Suh},
  journal={Neuroreport},
  year={1997},
  volume={8 7},
  pages={1733-7}
}
Patients with Alzheimer's disease (AD) show loss of memory and cognitive deficits the molecular mechanisms of which are not completely known. We examined age-related changes in the expression levels of beta-amyloid precursor protein (beta APP) in the brain of the senescence accelerated mouse (SAM) P/10, which shows age-dependent brain atrophy and impairment… CONTINUE READING