Age-related changes in the content of non-reducible crosslinks in rat mandibular bone.

@article{Shikata1985AgerelatedCI,
  title={Age-related changes in the content of non-reducible crosslinks in rat mandibular bone.},
  author={Hiroo Shikata and Midori Hiramatsu and Toshiki Masumizu and Drs Isaburo Fujimoto and Nobuo Utsumi},
  journal={Archives of oral biology},
  year={1985},
  volume={30 5},
  pages={451-3}
}
Age-related changes in the content of non-reducible crosslink amino acids, pyridinoline and histidinoalanine, in rat mandibular bone were studied. The pyridinoline content markedly increased up to 12 months of age and thereafter slightly increased. The histidinoalanine content was low until 3 months of age, but thereafter increased significantly up to 24 months. Total collagen content remained constant throughout the experiment. From these results, pyridinoline and histidinoalanine may serve as… CONTINUE READING

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