Age-related changes in melatonin release in the murine distal colon.

Abstract

Constipation and fecal impaction are conditions of the bowel whose prevalence increases with age. Limited information is known about how these conditions manifest; however, functional deficits are likely to be due to changes in signaling within the bowel. This study investigated the effects of age on colonic mucosal melatonin (MEL) release and the… (More)
DOI: 10.1021/cn4000617

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