Age-related changes in expression of CTL2/SLC44A2 and its isoforms in the mouse inner ear.

@article{Beyer2011AgerelatedCI,
  title={Age-related changes in expression of CTL2/SLC44A2 and its isoforms in the mouse inner ear.},
  author={Lisa A. Beyer and Maria M. Galano and Thankam S. Nair and Pavan K. Kommareddi and Su-Hua Sha and Yehoash Raphael and Thomas E. Carey},
  journal={Hearing research},
  year={2011},
  volume={282 1-2},
  pages={63-8}
}
The membrane glycoprotein CTL2/SLC44A2 is expressed by supporting cells in the inner ear and has been identified as a target of antibodies that may induce auto-immune hearing loss. To determine if CTL2/SLC44A2 also has roles in inner ear development and to distinguish between isoform-specific roles, we assessed age-related changes in expression of CTL2/SLC44A2 isoforms and protein in the developing murine inner ear. We determined that both isoform p1 and isoform p2 (named for the upstream p1… CONTINUE READING