Age-related changes in enzymes of rat brain. 2. Redox systems linked to NADP and glutathione.


Measurements have been made of the enzymes of glutathione metabolism and of NADPH generation in the brains of rats aged between 1 day and 24 months. The activity of glutathione peroxidase fell while that of glutathione reductase rose during the aging process. The four NADPH-generating systems each showed a different profile with respect to aging, the most… (More)


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