Age-related changes in basal dendrite and dendritic spine of hippocampal pyramidal neurons (CA1) among SAMP1TA/Ngs--quantitative analysis by the rapid Golgi method.

@article{Kawaguchi1995AgerelatedCI,
  title={Age-related changes in basal dendrite and dendritic spine of hippocampal pyramidal neurons (CA1) among SAMP1TA/Ngs--quantitative analysis by the rapid Golgi method.},
  author={Sachiko Kawaguchi and Masao Kishikawa and Mayuko Sakae and Yoshibumi Nakane},
  journal={Mechanisms of ageing and development},
  year={1995},
  volume={83 1},
  pages={11-20}
}
It has been confirmed that a substrain of the senescence-accelerated mouse SAMP1TA/Ngs develops learning disturbance-like behavior at 3 months of age, exhibits almost normal behavior at 5 months, and manifests learning disturbance at 7 months. The changes with age in basal dendrites and dendritic spines of CA1 pyramidal neurons were quantitatively evaluated… CONTINUE READING