Age-related change of neurochemical abnormality in attention-deficit hyperactivity disorder: a meta-analysis.

@article{Aoki2013AgerelatedCO,
  title={Age-related change of neurochemical abnormality in attention-deficit hyperactivity disorder: a meta-analysis.},
  author={Yuta Aoki and Ryota Inokuchi and Hiroshi Suwa and Ai Aoki},
  journal={Neuroscience and biobehavioral reviews},
  year={2013},
  volume={37 8},
  pages={1692-701}
}
Prevalence and symptoms of attention-deficit hyperactivity disorder (ADHD) change with advancing age. However, neurochemical background of such age-related change is yet to be elucidated. We therefore conducted a meta-analysis of 16 proton magnetic resonance spectroscopy studies comprising 270 individuals with ADHD and 235 controls. Standardized mean differences were calculated and used as an effect size. Sensitivity analyses and meta-regression to explore the effect of age on neurochemical… CONTINUE READING