Age-related base excision repair activity in mouse brain and liver nuclear extracts.

Abstract

To assess DNA repair activity relative to age, in vitro base excision repair assays were performed using brain and liver nuclear extracts prepared from mice of various ages. An 85% decline in repair activity was observed in brain nuclear extracts and a 50% decrease in liver nuclear extracts prepared from old mice compared with 6-day-old mice. Brain nuclear… (More)

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.