Age of methylphenidate treatment initiation in children with ADHD and later substance abuse: prospective follow-up into adulthood.

@article{Mannuzza2008AgeOM,
  title={Age of methylphenidate treatment initiation in children with ADHD and later substance abuse: prospective follow-up into adulthood.},
  author={Salvatore Mannuzza and Rachel G. Klein and Nhan L Truong and John L Moulton and Erica R Roizen and Kathryn H. Howell and F. Xavier Castellanos},
  journal={The American journal of psychiatry},
  year={2008},
  volume={165 5},
  pages={604-9}
}
OBJECTIVE Animal studies have shown that age at stimulant exposure is positively related to later drug sensitivity. The purpose of this study was to examine whether age at initiation of stimulant treatment in children with attention deficit hyperactivity disorder (ADHD) is related to the subsequent development of substance use disorders. METHOD The authors conducted a prospective longitudinal study of 176 methylphenidate-treated Caucasian male children (ages 6 to 12) with ADHD but without… CONTINUE READING
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