Age-of-asthma onset as a determinant of different asthma phenotypes in adults: a systematic review and meta-analysis of the literature

  title={Age-of-asthma onset as a determinant of different asthma phenotypes in adults: a systematic review and meta-analysis of the literature},
  author={Daniel J. Tan and Eugene Haydn Walters and Jennifer L. Perret and Caroline J. Lodge and Adrian J. Lowe and Melanie C Matheson and S. Dharmage},
  journal={Expert Review of Respiratory Medicine},
  pages={109 - 123}
Age-of-asthma onset is often used to distinguish different adult asthma phenotypes; however, similarities and differences between early- and late-onset adult asthma have not been summarized to date. Of the 2921 records found, we identified 12 studies comparing early- and late-onset current asthma in adults. Age 12 was most commonly used to delineate the two age-of-onset phenotypes. Adults with early-onset current asthma were more likely to be atopic and had a higher frequency of asthma attacks… 
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