Age modifies the genotype-phenotype relationship for the bitter receptor TAS2R38

@inproceedings{Mennella2009AgeMT,
  title={Age modifies the genotype-phenotype relationship for the bitter receptor TAS2R38},
  author={Julie A Mennella and Marta Yanina Pepino and Fujiko F. Duke and Danielle R Reed},
  booktitle={BMC Genetics},
  year={2009}
}
The purpose of this study was to investigate the effect of TAS2R38 haplotypes and age on human bitter taste perception. Children (3 to 10 yrs), adolescents (11 to 19 yrs) and adults (mostly mothers, 20 to 55 yrs (N = 980) were measured for bitter taste thresholds for 6-n-propylthiouracil (PROP) and genotyped for three polymorphisms of the AS2R38 gene (A49P, V262A, I296V). Subjects were grouped by haplotype and age, as well as sex and race/ethnicity, and compared for PROP thresholds. Subjects… CONTINUE READING
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