Age-linked changes in the activity of enzymes of the tricarboxylate cycle and lipid oxidation, and of carnitine content, in muscles of the rat.

@article{Hansford1982AgelinkedCI,
  title={Age-linked changes in the activity of enzymes of the tricarboxylate cycle and lipid oxidation, and of carnitine content, in muscles of the rat.},
  author={Richard G N Hansford and Francesc Castro},
  journal={Mechanisms of ageing and development},
  year={1982},
  volume={19 2},
  pages={191-200}
}
The activities of citrate synthase, NAD-isocitrate dehydrogenase and 2-oxoglutarate dehydrogenase were measured in homogenates of soleus, diaphragm and heart muscles of the rat, in an attempt to define potential tricarboxylate cycle activity and its response to aging. Activities were significantly decreased in 24-month animals versus 6-month controls in… CONTINUE READING