Age differences in an animal model of obsessive-compulsive disorder: participation of dopamine: dopamine in an animal model of OCD.

@article{Ulloa2004AgeDI,
  title={Age differences in an animal model of obsessive-compulsive disorder: participation of dopamine: dopamine in an animal model of OCD.},
  author={R. Z. Ulloa and Humberto Nicolini and Alonso Fern{\'a}ndez-Guasti},
  journal={Pharmacology, biochemistry, and behavior},
  year={2004},
  volume={78 4},
  pages={661-6}
}
The putative age difference in the effect of chronically administered quinpirole (0.125 and 0.5 mg/kg, 11 injections) on alternation in a T maze was studied. Male juvenile (43 days old) and adult (around 90 days old) rats exhibited similar control values of alternation. In adults, quinpirole (0.5 mg/kg) produced a drastic perseveration after 10 and 11… CONTINUE READING