Age-dependent suppression of nocturnal growth hormone levels during sleep deprivation.

@article{Mullington1996AgedependentSO,
  title={Age-dependent suppression of nocturnal growth hormone levels during sleep deprivation.},
  author={Janet M Mullington and Dirk M. Hermann and Florian Holsboer and Thomas Pollm{\"a}cher},
  journal={Neuroendocrinology},
  year={1996},
  volume={64 3},
  pages={
          233-41
        }
}
Although the major daily peak in plasma growth hormone (GH) level normally occurs during the early part of nocturnal sleep, it is known that in about one quarter of young healthy men, peaks in circulating human GH occur before sleep onset. Possible factors associated with these nocturnal peaks were investigated in the absence of sleep, including subjectively defined sleepiness, electroencephalographically defined drowsiness and short lapses into sleep, measures of cortisol and temperature… 

Adaptation of the 24-h growth hormone profile to a state of sleep debt.

Neither the GH profile nor the distribution of SWA conformed with predictions from acute sleep deprivation studies, indicating that adaptation mechanisms are operative during chronic partial sleep loss.

Interactions Between Growth Hormone Secretion and Sleep

The sleep-wake transition in the human is generally associated with more pronounced variations in endocrine, metabolic, and other parameters than in other species.

Sleep Characteristics in Children with Growth Hormone Deficiency

The analysis of sleep microstructure by means of CAP, in children with GHD, showed a reduction of transient EEG amplitude oscillations, represented by a significant global decrease in the CAP rate, involving all CAP A phase subtypes.

Diurnal variations and sleep deprivation-induced changes in rat hypothalamic GHRH and somatostatin contents.

Comparisons of the present results with previously reported changes in hypothalamic GHRH mRNA suggest that periods of deep nonrapid eye movement sleep (first portion of the light period and recovery sleep after SD) are associated with intense hypothalamicGHRH release.

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Reciprocal interactions between the GH axis and sleep.

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Sleep Loss Reduces Diurnal Rhythm Amplitude of Leptin in Healthy Men

Evidence that sleep influences the nocturnal leptin profile is provided, and may have implications for the understanding of the role of sleep in metabolic regulation and the aetiologies of obesity and the night eating syndrome.

Endocrinology of Sleep

The goal of this chapter is to review the regulation of the endocrine system during sleep as well as the impact of various endocrine loops upon sleep initiation, maintenance, and architecture.
...

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