Age dependent shifts in renal response to injury relate 1 to altered BMP 6 / CTGF expression and signaling 2 3

Abstract

33 Age is associated with an increased prevalence of chronic kidney disease (CKD), which, 34 through progressive tissue damage and fibrosis, ultimately leads to loss of kidney 35 function. Although much effort is put into studying CKD development experimentally, 36 age has rarely been taken into account. Therefore, we investigated the effect of age on 37… (More)

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