Age-dependent micronuclear deterioration in Tetrahymena pyriformis, syngen 1.

Abstract

In the ciliate Tetrahymena pyriformis, syngen 1, senescence is marked both by mitotic and meiotic cytogenetic irregularities of the micronucleus (germinal nucleus) and by an increased frequency of cell death. Full vigor can be restored through the age-dependent process of genomic exclusion, which in prematurely senscent clones C, A III and A V results in… (More)

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