Age-dependent increase of etheno-DNA-adducts in liver and brain of ROS overproducing OXYS rats.

@article{Nair2005AgedependentIO,
  title={Age-dependent increase of etheno-DNA-adducts in liver and brain of ROS overproducing OXYS rats.},
  author={J. Hariharan Nair and Olga I. Sinitsina and Elena A Vasunina and Georgy A Nevinsky and J. Laval and Helmut Bartsch},
  journal={Biochemical and biophysical research communications},
  year={2005},
  volume={336 2},
  pages={478-82}
}
Reactive oxygen species (ROS) and lipid peroxidation (LPO) play a role in aging and degenerative diseases. To correlate oxidative stress and LPO-derived DNA damage, we determined etheno-DNA-adducts in liver and brain from ROS overproducing OXYS rats in comparison with age-matched Wistar rats. Liver DNA samples from 3- and 15-month-old OXYS and Wistar rats… CONTINUE READING