Age-dependent effects of neonatal methamphetamine exposure on spatial learning.

@article{Vorhees2007AgedependentEO,
  title={Age-dependent effects of neonatal methamphetamine exposure on spatial learning.},
  author={Charles V Vorhees and M R Skelton and Michael T Williams},
  journal={Behavioural pharmacology},
  year={2007},
  volume={18 5-6},
  pages={549-62}
}
Neonatal rats exposed to (+)-methamphetamine (MA) display spatial learning and reference memory deficits in the Morris water maze. In separate experiments the emergence and permanence of these effects were determined. Twenty litters were used in each experiment, and two male/female pairs/litter received saline or MA (5 mg/kg four times a day) on postnatal days (P) 11-20. In experiment 1, one MA and one saline pair from each litter began testing on either P30 or P40, whereas in experiment 2… CONTINUE READING

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