Age-dependent decline in erythrocyte acetylcholinesterase activity: correlation with oxidative stress.

@article{Jha2009AgedependentDI,
  title={Age-dependent decline in erythrocyte acetylcholinesterase activity: correlation with oxidative stress.},
  author={Rashmi Jha and Syed Ibrahim Rizvi},
  journal={Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia},
  year={2009},
  volume={153 3},
  pages={195-8}
}
BACKGROUND Oxidative stress hypothesis offers a mechanism for the aging process and its involvement in other pathologies such as diabetes and neurodegenerative diseases like Alzheimer. AChE activity in erythrocytes may be considered as a marker of central cholinergic status. The present study was undertaken to (i) determine the activity of erythrocyte AChE as a function of human process (ii) correlate AChE activity with oxidative stress during human aging. MATERIAL AND METHODS Blood was… CONTINUE READING