Age-dependent chloride channel expression in skeletal muscle fibres of normal and HSA(LR) myotonic mice.

Abstract

Abstract  We combine electrophysiological and optical techniques to investigate the role that the expression of chloride channels (ClC-1) plays on the age-dependent electrical properties of mammalian muscle fibres. To this end, we comparatively evaluate the magnitude and voltage dependence of chloride currents (ICl), as well as the resting resistance, in… (More)
DOI: 10.1113/jphysiol.2012.246546

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