Age but not ABCD2 score predicts any level of carotid stenosis in either symptomatic or asymptomatic side in transient ischaemic attack

@article{Mannu2015AgeBN,
  title={Age but not ABCD2 score predicts any level of carotid stenosis in either symptomatic or asymptomatic side in transient ischaemic attack},
  author={Gurdeep S. Mannu and Myint Myint Kyu and Joao H. Bettencourt-Silva and Yoon Kong Loke and Allan B Clark and Anthony Kneale Metcalf and John F. Potter and Phyo Kyaw Myint},
  journal={International Journal of Clinical Practice},
  year={2015},
  volume={69}
}
  • G. Mannu, M. Kyu, P. Myint
  • Published 1 September 2015
  • Medicine
  • International Journal of Clinical Practice
The ABCD2 score is routinely used in assessment of transient ischaemic attack (TIA) to assess the risk of developing stroke. There remains uncertainty regarding whether the ABCD2 score could be used to help predict extent of carotid artery stenosis (CAS). 

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Logistic regression analysis shows that age, diabetes, and low-density lipoprotein cholesterol are independent risk factors for CAS in the high-risk population of stroke in this area.

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Performance of the ABCD and ABCD2 Scores in TIA Patients with Carotid Stenosis and Atrial Fibrillation

TLDR
The ABCD and ABCD2 risk scores appear to identify patients with ≧50% carotid stenosis or AF who are at high risk of stroke, and these findings should be interpreted with caution due to the small number of outcomes among these subgroups.

Population-Based Study of ABCD2 Score, Carotid Stenosis, and Atrial Fibrillation for Early Stroke Prediction After Transient Ischemic Attack: The North Dublin TIA Study

TLDR
The ABCD2 score had predictive utility in patients with TIA suspected by nonspecialists, and low scores occurred in several patients with stroke recurrences, suggesting that caution is needed before using the score in isolation.

Contributions Population-Based Study of ABCD 2 Score , Carotid Stenosis , and Atrial Fibrillation for Early Stroke Prediction After Transient Ischemic Attack The North Dublin TIA Study

TLDR
The ABCD score had predictive utility in patients with TIA suspected by nonspecialist-suspected TIA cases, and in a population-based TIA cohort, significant predictive information was provided by carotid stenosis.

Triaging TIA/minor stroke patients using the ABCD2 score does not predict those with significant carotid disease.

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TLDR
Evidence-based recommendations are included for the control of risk factors, interventional approaches to atherosclerotic disease of the cervicocephalic circulation, and antithrombotic treatments for preventing thrombosis and thromboembolic stroke.

Screening for carotid artery stenosis: U.S. Preventive Services Task Force recommendation statement.

TLDR
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Prognostic value of the ABCD² clinical prediction rule: a systematic review and meta-analysis.

TLDR
The ABCD² is a useful CPR, particularly in relation to 7-day risk of stroke, and there is a non-significant trend towards over-prediction of stroke in all risk categories at 90 days.