Age-based comparison of human dendritic spine structure using complete three-dimensional reconstructions.

@article{BenavidesPiccione2013AgebasedCO,
  title={Age-based comparison of human dendritic spine structure using complete three-dimensional reconstructions.},
  author={Ruth Benavides-Piccione and Isabel Fernaud-Espinosa and V{\'i}ctor Robles and Rafael Yuste and Javier DeFelipe},
  journal={Cerebral cortex},
  year={2013},
  volume={23 8},
  pages={1798-810}
}
Dendritic spines of pyramidal neurons are targets of most excitatory synapses in the cerebral cortex. Recent evidence suggests that the morphology of the dendritic spine could determine its synaptic strength and learning rules. However, unfortunately, there are scant data available regarding the detailed morphology of these structures for the human cerebral cortex. In the present study, we analyzed over 8900 individual dendritic spines that were completely 3D reconstructed along the length of… CONTINUE READING
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