Age at onset of epilepsy, pharmacoresistance, and cognitive outcomes: a prospective cohort study.

@article{Berg2012AgeAO,
  title={Age at onset of epilepsy, pharmacoresistance, and cognitive outcomes: a prospective cohort study.},
  author={Anne T. Berg and Frank A Zelko and Susan R Levy and Francine M Testa},
  journal={Neurology},
  year={2012},
  volume={79 13},
  pages={1384-91}
}
OBJECTIVES Increasing evidence suggests that uncontrolled seizures have deleterious effects on cognition and behavior, particularly in the developing brain. METHODS In a community-based cohort, 198 children, aged <8 years with new-onset epilepsy were followed prospectively and reassessed with the Wechsler Intelligence Scales for Children, Third Edition (WISC-III) 8-9 years later. Linear regression analyses with interactions between age at onset (age) and pharmacoresistance (PR) were used to… CONTINUE READING