Age-associated decrease in serum glial cell line-derived neurotrophic factor levels in patients with major depressive disorder

@article{Tseng2013AgeassociatedDI,
  title={Age-associated decrease in serum glial cell line-derived neurotrophic factor levels in patients with major depressive disorder},
  author={Ping-Tao Tseng and Yu Lee and Pao-Yen Lin},
  journal={Progress in Neuro-Psychopharmacology and Biological Psychiatry},
  year={2013},
  volume={40},
  pages={334-339}
}
BACKGROUND Many studies have supported the role of neurotrophic hypothesis in the pathophysiology of mood disorders. This study examined serum levels of glial cell line-derived neurotrophic factor (GDNF), one of the neurotrophic factors, in patients with major depressive disorder (MDD) at different disease states. METHODS The serum GDNF levels were measured in 55 patients with MDD (29 severe patients and 26 remitted patients) and 35 healthy controls by ELISA method. Severity of depressive… CONTINUE READING

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