Age-associated decline in natural killer (NK) activity reflects primarily a defect in function of NK cells.


The possible role that natural killer (NK) cells might play in the control of tumors and certain infections prompted an investigation of the status of NK cells in aged mice of two inbred strains (C3H and C57BL/6). The frequency of NK cells in young-adult and aged mice was assessed by two methods that provided accurate estimates of the relative numbers of NK… (More)