Age associated changes in intracellular cyclic adenosine monophosphate.

Cyclic adenosine monophosphate (cAMP) levels of isolated human peripheral blood lymphocytes show age associated changes. These changes are apparent in basal cAMP levels as well as in cAMP levels after trypsin treatment. Both cord blood lymphocytes and lymphocytes isolated from the blood of old people exhibit lower basal levels of cAMP and diminished… CONTINUE READING