Age-associated alterations in thirst and arginine vasopressin in response to a water or sodium load.

@article{Davies1995AgeassociatedAI,
  title={Age-associated alterations in thirst and arginine vasopressin in response to a water or sodium load.},
  author={Ian Davies and P. O'Neill and Kathy A McLean and Joe Catania and Derrick C Bennett},
  journal={Age and ageing},
  year={1995},
  volume={24 2},
  pages={151-9}
}
We have examined simultaneous changes in thirst, plasma osmolality and arginine vasopressin, after oral water loading or hypertonic saline infusion. The studies were carried out in the same subjects, comprising young controls aged 26.8 years (SD 4.8, n = 10) and health status-defined elderly people aged 72.1 years (SD 3.1, n = 10). Water loading caused significant falls in plasma osmolality (p < 0.001) and thirst (p < 0.001), but there was no variation with age. Infusion with 462 mmol/l of… CONTINUE READING

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