Age-associated alterations in cortical gray and white matter signal intensity and gray to white matter contrast

@article{Salat2009AgeassociatedAI,
  title={Age-associated alterations in cortical gray and white matter signal intensity and gray to white matter contrast},
  author={David H. Salat and Stephanie Y. Lee and Andr{\'e} J. W. van der Kouwe and Douglas N. Greve and Bruce Fischl and H. Diana Rosas},
  journal={NeuroImage},
  year={2009},
  volume={48 1},
  pages={21-8}
}
Prior studies have focused on patterns of brain atrophy with aging and age-associated cognitive decline. It is possible that changes in neural tissue properties could provide an important marker of more subtle changes compared to gross morphometry. However, little is known about how MRI tissue parameters are altered in aging. We created cortical surface models of 148 individuals and mapped regional gray and white matter T1-weighted signal intensities from 3D MPRAGE images to examine patterns of… CONTINUE READING
Highly Influential
This paper has highly influenced 11 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
92 Citations
67 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 92 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 67 references

Cerebral correlates of cognitive aging: gray–whitematter differentiation in the medial temporal lobes, and fluid versus crystallized abilities

  • N. Raz, D. Millman, G. Sarpel
  • Psychobiology
  • 1990
Highly Influential
5 Excerpts

Similar Papers

Loading similar papers…