Age-associated abnormalities of water homeostasis.

  title={Age-associated abnormalities of water homeostasis.},
  author={Laura E Cowen and Steven P. Hodak and Joseph G. Verbalis},
  journal={Endocrinology and metabolism clinics of North America},
  volume={42 2},
Findley first proposed the presence of age-related dysfunction of the hypothalamic-neurohypophyseal-renal axis more than 60 years ago. More sophisticated studies have since corroborated his findings. As a result, it is now clear that multiple abnormalities in water homeostasis occur commonly with aging, and that the elderly are uniquely susceptible to disorders of body volume and osmolality. This article summarizes the distinct points along the hypothalamic-neurohypophyseal-renal axis where… CONTINUE READING


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