Age and nutritional state influence the effects of cholecystokinin on energy balance

@article{Balask2013AgeAN,
  title={Age and nutritional state influence the effects of cholecystokinin on energy balance},
  author={M{\'a}rta Balask{\'o} and Ildik{\'o} Rost{\'a}s and N{\'o}ra F{\"u}redi and Alexandra Mik{\'o} and Judit Tenk and Peter Cseplo and Margit Koncsecsk{\'o}-G{\'a}sp{\'a}r and Sz So{\'o}s and M Sasvari- Szekely and Erika P{\'e}terv{\'a}ri},
  journal={Experimental Gerontology},
  year={2013},
  volume={48},
  pages={1180-1188}
}
Cholecystokinin (CCK) is anorexic, irrespective whether it is applied intraperitoneally (IP) or intracerebroventricularly (ICV) in male Wistar rats. The metabolic effects depend on the route of administration: by the IP route it elicits hypothermia (presumably by type-1 receptors, CCK1R-s), while ICV administration is followed by fever-like hypermetabolism and hyperthermia via activation of CCK2R-s, which latter response seems to be most important in the postprandial (compensatory… CONTINUE READING

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