Age- and gender-related elastin distribution changes in human vocal folds

@article{Hammond1998AgeAG,
  title={Age- and gender-related elastin distribution changes in human vocal folds},
  author={Thomas Hale Hammond and Steven D. Gray and John E. Butler and R Zhou and Elizabeth H. Hammond},
  journal={Otolaryngology- Head and Neck Surgery},
  year={1998},
  volume={119},
  pages={314 - 322}
}
The composition of the lamina propria in human vocal folds has been shown to affect vocal performance. Elastin plays a significant role in the biomechanical effects of the lamina propria. We obtained 19 larynges from the state medical examiner from subjects whose cause of death was unrelated to the trachea and laryngeal regions. The sample contained male and female subjects in the infant, adult, and geriatric age groups. We stained the vocal folds for elastin with Verhoeff's elastic tissue… 
Age- and Gender-Related Collagen Distribution in Human Vocal Folds
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There are age-related and gender-related differences between male and female infant, adult, and geriatric vocal folds, and distribution pattern of collagen showed that most of the collagen was present in the deep layer.
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The decrease in the thickness of the lamina propria of the vocal folds with aging may contribute to the vocal pattern present in the elderly.
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Investigation of the structure of the VF of elderly people that may contribute to the tendency of the human voice to deteriorate revealed that the collagenous component of the deep layer ofThe VF LP was made up of mature fibers whilst immature collagen fibers made up the superficial layer of the LP.
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Relative Contributions of Collagen and Elastin to Elasticity of the Vocal Fold Under Tension
TLDR
It is suggested that collagen and elastin could contribute differentially to elasticity of the cover and the ligament, which may provide guidance for surgical reconstruction and tissue engineering of different lamina propria layers.
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TLDR
A preliminary gender-related difference in elasticity could be attributed to a higher proportion of glandular tissue in the female false fold, due to the lower elastic modulus of glands, to develop a more comprehensive biomechanical model of phonation.
Insights into the role of elastin in vocal fold health and disease.
TLDR
An overview of the genesis of elastin and its wide-ranging structure and function is provided and specific distribution within the vocal fold lamina propria across the lifespan in normal and pathological states and its contribution to vocal fold biomechanics will be examined.
Collagen Subtypes in Human Vocal Folds
TLDR
The results suggest that type III fibers help maintain the lamina propria structure and that type I fibers provide the tensile strength required around the basal membrane and vocal ligament to maintain the vocal fold shape while withstanding vibratory forces.
Lamina propria of the human vocal fold: histomorphometric study of collagen fibers
TLDR
These results help describe the distribution of collagen fibers within the lamina propria of the human vocal fold and have implications to understand the cover-body theory of voice production both in the adult and newborn.
Quantitative and Comparative Studies of the Vocal Fold Extracellular Matrix I: Elastic Fibers and Hyaluronic Acid
TLDR
The elastin content of the human LP is roughly twice that of the dermis, whereas the HAcontent of thehuman LP is similar to that ofThe dermis.
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